Epigenetic’s Science is written by award winning author, Raoul Pedretta. Great bye, genetically encoded genes… the first book in the exciting new field of epigenetic biology for general readers. The surging new science of epigenetic genetics offers a veritable cornucopia of new insights into our bodies and minds – some unsettling, some reassuring. The assumption of Epigenetic’s Science is that environmental exposures can have long lasting effects on cellular function. Some of these effects are not very easy to reverse and the authors describe how”epigenetic inheritance” can result in such illnesses as cancer, Alzheimer’s disease and Parkinson’s. They also clarify the surprising effect of”epigenetic pollution,” environmental contaminants that aren’t detected by regular testing and that could cause severe health problems.
Like all living systems, cells are constantly changing and grow, divide and die. All cells require a constant supply of energy, and this process is initiated by a process called”mimetic induction”. Through natural selection, favorable mutations accumulate over generations, and if they get together, these cells form a type of cellular memory, or methylation state. This methylation state is passed on between generations and determines how cells in one family will behave in response to environmental challenges and how those cells will react when similar challenges arise in another household member.
When methylation is induced in a cell, the result may be a whole gamut of changes on the cell surface and in the biochemical pathways within the cell. This results in alterations in gene function and a corresponding reaction physically. There are many ways in which Epigenetic’s Science presents the science of Epigenetics. By way of instance, each chapter contains an informative section covering among the most frequent Epigenetic changes that exist in all people: puberty. The chapters include;”Growthal Sensitivity,””Mutations in Birth,”” hormonal changes,””perinatal development,””adolescent-onset diabetes,” and”nutrition.” I enjoyed each of these and found them to be very interesting and educational.
As you know, during adolescence, the body increases its production of estrogen (in anticipation of future pregnancy), and then, produces DHT (which stands for”dihydrotestosterone”). DHT then binds to the hair follicles, which makes it difficult for nutrients to reach the roots. This causes baldness in a condition called”male pattern baldness” Interestingly, this isn’t the only cause of hair loss, since there are other genetic and environmental factors that contribute to hair loss. Epigenetic science goes a step further and suggests that these other causes of hair loss may also be influenced by methylation, so future study might shed more light on Epigenetic’s Science.
The next topic that Epigenetic’s Science touches on is the effect that diet has on the body. In particular, Epigenetic’s Science goes into detail concerning the impact that diet has on mice, worms, and other organisms. To start with, one interesting finding was that when the worm C. elegans has been given a high fat diet, it became obese and diabetic. Interestingly, the lab animals also lost muscle mass, which is indicative of insulin resistance. In another experiment, the laboratory animals were put on a particular sort of diet where they just received food that contained carbohydrates; they lost body fat fairly quickly.
So as to understand what is happening here, you have to have a look at the Epigenetic’s Science methodology. Basically, they’re growing yeast in lab cultures and watching what happens. When the yeast grows to a certain point, it will replicate and thus create a new generation of yeast cells. In this case, the generation of cells was used to study insulin resistance, something that we humans have.
Of course, there are additional Epigenetic’s Science techniques they use, including gene regulation and the analysis of cancerous tumors. In fact, they’ve recently established a successful clinical trial where they are attempting to treat Alzheimer’s disease in mice. As exciting as that may sound, it’s not your regular normal cancer therapy. This study shows they are able to control and regulate cells and halt the growth of cancerous tumors.
Besides diabetes, Epigenetic’s Science can be used for other types of diseases and conditions, such as Parkinson’s, arthritis, Multiple Sclerosis, and even cancer. Of course, these studies are extremely small so we do not have much of a sense of what they will mean for human health. Still, it’s an exciting and very promising prospect. Just think, one day you might have the ability to grow your own cells for immune system support and energy generation; essentially creating your very own drug factory!