Epigenetic’s Science is written by award winning author, Raoul Pedretta. Good bye, genetically encoded genes… the first book in the exciting new field of epigenetic biology for general readers. The surging new science of epigenetic genetics provides a veritable cornucopia of fresh insights into our bodies and minds – some unsettling, some reassuring. The premise of Epigenetic’s Science is the fact that environmental exposures can have long lasting effects on cellular function. Some of these effects aren’t so easy to reverse and the authors describe how”epigenetic inheritance” can result in such illnesses as cancer, Alzheimer’s disease and Parkinson’s. They also clarify the surprising effect of”epigenetic pollution,” environmental contaminants that are not detected by regular testing and that could cause severe health problems.
Like all living systems, cells are constantly changing and grow, divide and die. All cells need a continuous supply of energy, and this process is initiated by a process referred to as”mimetic induction”. Through natural selection, positive mutations accumulate over generations, and when they get together, these cells form a type of cellular memory, or methylation state. This methylation state is passed on between generations and determines how cells in 1 family will act in response to environmental challenges and how those cells will react when similar challenges arise in a different family member.
When methylation is induced in a cell, the result may be a whole gamut of changes on the cell surface and in the biochemical pathways within the cell. This results in alterations in gene function and a corresponding reaction physically. There are many ways that Epigenetic’s Science presents the science of Epigenetics. For example, each chapter includes an informative section addressing one of the most frequent Epigenetic changes that exist in all people: puberty. The chapters comprise;”Growthal Sensitivity,””Mutations in Birth,”” hormonal changes,””perinatal development,””adolescent-onset diabetes,” and”nutrition.” I enjoyed each of these and found them to be quite interesting and educational.
As you know, during adolescence, the body increases its production of estrogen (in anticipation of future pregnancy), and then, produces DHT (which stands for”dihydrotestosterone”). DHT subsequently binds to the hair follicles, which makes it difficult for nutrients to reach the roots. This causes baldness in men and a condition known as”male pattern baldness” Interestingly, this isn’t the only cause of hair loss, as there are other environmental and genetic factors that contribute to hair loss. Epigenetic science goes a step further and suggests that these other causes of hair loss may also be influenced by methylation, so future research might shed even more light on Epigenetic’s Science.
The next topic that Epigenetic’s Science touches on is the impact that diet has on the body. Specifically, Epigenetic’s Science goes into detail concerning the effect that diet has on rats, rodents, and other organisms. To begin with, one interesting finding was that when the worm C. elegans has been given a high fat diet, it became obese and diabetic. Interestingly, the laboratory animals also lost muscle mass, which is indicative of insulin resistance. In another experiment, the laboratory animals were put on a particular type of diet where they just received food that contained carbohydrates; they lost body fat fairly quickly.
So as to understand what’s happening here, you must take a look at the Epigenetic’s Science methodology. Basically, they are growing yeast in laboratory cultures and watching what happens. When the yeast grows to a certain point, it is going to replicate and thus create a new generation of yeast cells. In cases like this, the creation of cells was used to study insulin resistance, something that we humans possess.
Needless to say, there are other Epigenetic’s Science techniques that they use, including gene regulation and the analysis of cancerous tumors. In fact, they have recently launched a successful clinical trial where they are trying to treat Alzheimer’s disease in mice. As exciting as that may seem, it’s not your regular normal cancer therapy. This study shows that they are able to control and regulate cells and stop the growth of cancerous tumors.
In addition to diabetes, Epigenetic’s Science may be used for other kinds of diseases and conditions, such as Parkinson’s, arthritis, Multiple Sclerosis, and even cancer. Needless to say, these studies are very small so we do not have much of a sense of what they will mean for human health. Still, it’s an exciting and very promising prospect. Just think, one day you could have the ability to grow your own cells for immune system support and energy production; essentially creating your very own drug factory!