Epigenetic’s Science is written by award winning writer, Raoul Pedretta. Good bye, genetically encoded genes… the first book in the exciting new field of epigenetic biology for general readers. The surging new science of epigenetic genetics provides a veritable cornucopia of fresh insights into our own bodies and minds – some unsettling, some comforting. The assumption of Epigenetic’s Science is that environmental exposures can have long lasting effects on cellular function. Some of these effects aren’t very easy to reverse and the authors describe how”epigenetic inheritance” can result in such disorders as cancer, Alzheimer’s disease and Parkinson’s. They also clarify the surprising effect of”epigenetic pollution,” environmental contaminants that aren’t detected by standard testing and that could cause serious health problems.
Like all living systems, cells are constantly changing and grow, divide and die. All cells need a continuous supply of energy, and this process is initiated by a process called”mimetic induction”. Through natural selection, favorable mutations accumulate over generations, and if they get together, these cells form a type of cellular memory, or methylation state. This methylation state is passed between generations and decides how cells in 1 family will behave in response to environmental challenges and how those cells will respond when similar challenges arise in a different household member.
When methylation is induced in a cell, the result can be a whole gamut of changes on the cell surface and in the biochemical pathways within the cell. This results in alterations in gene function and a corresponding response physically. There are a number of ways in which Epigenetic’s Science presents the science of Epigenetics. By way of example, each chapter contains an informative section addressing one of the most frequent Epigenetic changes which exist in all of us: puberty. The chapters comprise;”Growthal Sensitivity,””Mutations at Birth,”” hormonal changes,””perinatal development,””adolescent-onset diabetes,” and”nutrition.” I enjoyed each of these and found them to be very interesting and educational.
As you know, during adolescence, the body increases its production of estrogen (in anticipation of future pregnancy), and then, produces DHT (which stands for”dihydrotestosterone”). DHT subsequently binds to the hair follicles, making it difficult for nutrients to reach the roots. This causes baldness in a condition called”male pattern baldness” Interestingly, this is not the only cause of hair loss, as there are other environmental and genetic factors that contribute to hair loss. Epigenetic science goes a step further and suggests that these other causes of hair loss may also be affected by methylation, so future study might shed even more light on Epigenetic’s Science.
The next topic that Epigenetic’s Science touches on is the impact that diet has on the body. In particular, Epigenetic’s Science goes into detail about the impact that diet has on rats, rodents, and other organisms. To begin with, one interesting finding was that when the worm C. elegans has been given a high fat diet, it became obese and diabetic. Interestingly, the laboratory animals also lost muscle mass, which is indicative of insulin resistance. In another experiment, the lab animals were put on a particular type of diet where they just received food that contained carbohydrates; they lost body weight fairly rapidly.
In order to understand what’s happening here, you have to take a look at the Epigenetic’s Science methodology. Basically, they’re growing yeast in lab cultures and watching what happens. When the yeast grows to a certain point, it will replicate and thus create a new production of yeast cells. In this case, the generation of cells was used to study insulin resistance, something that we humans have.
Needless to say, there are additional Epigenetic’s Science techniques that they use, such as gene regulation and the study of cancerous tumors. In actuality, they have recently launched a successful clinical trial in which they’re trying to treat Alzheimer’s disease in mice. As exciting as that may seem, it’s not your regular normal cancer treatment. This study shows that they are able to control and regulate cells and halt the growth of cancerous tumors.
In addition to diabetes, Epigenetic’s Science may be used for other kinds of diseases and ailments, such as Parkinson’s, arthritis, Multiple Sclerosis, and even cancer. Of course, these studies are very small so we don’t have much of a sense of what they will mean for human health. Still, it’s an exciting and very promising prospect. Just think, one day you could be able to grow your own cells for immune system support and energy production; essentially creating your own drug factory!