Epigenetic’s Science is composed by award winning writer, Raoul Pedretta. Great bye, genetically encoded genes… the first book in the exciting new field of epigenetic biology for general readers. The surging new science of epigenetic genetics offers a veritable cornucopia of new insights into our own bodies and minds – some unsettling, some reassuring. The premise of Epigenetic’s Science is the fact that environmental exposures can have long lasting effects on cellular function. Some of these effects are not very easy to reverse and the authors describe how”epigenetic inheritance” can result in such illnesses as cancer, Alzheimer’s disease and Parkinson’s. They also clarify the surprising effect of”epigenetic pollution,” environmental contaminants that are not detected by standard testing and that can cause serious health problems.
Like all living systems, cells are constantly changing and grow, divide and die. All cells require a constant supply of energy, and this process is initiated by a process called”mimetic induction”. Through natural selection, positive mutations accumulate over generations, and if they get together, these cells form a sort of cellular memory, or methylation state. This methylation state is passed on between generations and decides how cells in one family will behave in response to environmental challenges and how those cells will respond when similar challenges arise in another household member.
When methylation is induced in a cell, the result can be a whole gamut of changes on the cell surface and in the biochemical pathways inside the cell. This causes alterations in gene function and a corresponding response on the body. There are many ways in which Epigenetic’s Science presents the science of Epigenetics. By way of instance, each chapter contains an informative section covering among the most frequent Epigenetic changes which exist in all of us: puberty. The chapters comprise;”Growthal Sensitivity,””Mutations in Birth,”” hormonal changes,””perinatal development,””adolescent-onset diabetes,” and”nutrition.” I enjoyed each of them and found them to be quite interesting and educational.
As you know, during adolescence, the body increases its production of estrogen (in anticipation of future pregnancy), and then, produces DHT (which stands for”dihydrotestosterone”). DHT subsequently binds to the hair follicles, which makes it difficult for nutrients to reach the roots. This causes baldness in a condition known as”male pattern baldness” Interestingly, this is not the only cause of hair loss, as there are other genetic and environmental factors that contribute to hair loss. Epigenetic science goes a step further and suggests that these other causes of hair loss may also be affected by methylation, so future study may shed even more light on Epigenetic’s Science.
The next topic that Epigenetic’s Science touches on is the effect that diet has on the body. Specifically, Epigenetic’s Science goes into detail concerning the effect that diet has on rats, rodents, and other organisms. To begin with, one interesting finding was that when the worm C. elegans was given a high fat diet, it became obese and diabetic. Interestingly, the laboratory animals also lost muscle mass, which is indicative of insulin resistance. In another experiment, the lab animals were put on a special type of diet where they just received food that contained carbohydrates; they lost body fat fairly rapidly.
In order to understand what’s going on here, you have to take a look at the Epigenetic’s Science methodology. Fundamentally, they are growing yeast in laboratory cultures and watching what happens. When the yeast grows to a certain point, it is going to replicate and thus create a new production of yeast cells. In cases like this, the creation of cells was used to study insulin resistance, something that we humans have.
Needless to say, there are additional Epigenetic’s Science techniques they use, such as gene regulation and the analysis of cancerous tumors. In actuality, they have recently established a successful clinical trial where they are attempting to treat Alzheimer’s disease in mice. As exciting as that may seem, it is not your everyday normal cancer therapy. This study shows they are able to manipulate and regulate cells and halt the growth of cancerous tumors.
In addition to diabetes, Epigenetic’s Science can be used for other types of diseases and ailments, such as Parkinson’s, arthritis, Multiple Sclerosis, and even cancer. Of course, these studies are extremely small so we don’t have much of a sense of what they will mean for human health. Still, it’s an exciting and very promising prospect. Just think, one day you might have the ability to grow your own cells for immune system support and energy generation; essentially creating your own drug factory!