Epigenetic’s Science is written by award winning writer, Raoul Pedretta. Good bye, genetically encoded genes… the first book in the exciting new field of epigenetic biology for general readers. The surging new science of epigenetic genetics offers a veritable cornucopia of fresh insights into our own bodies and minds – some unsettling, some reassuring. The assumption of Epigenetic’s Science is that environmental exposures can have long lasting effects on cellular function. Some of these effects aren’t very easy to reverse and the authors describe how”epigenetic inheritance” can lead to such illnesses as cancer, Alzheimer’s disease and Parkinson’s. They also describe the surprising effect of”epigenetic pollution,” environmental contaminants that aren’t detected by regular testing and that can cause severe health issues.
Like all living systems, cells are constantly changing and grow, divide and die. All cells need a constant supply of energy, and this process is initiated by a process called”mimetic induction”. Through natural selection, positive mutations accumulate over generations, and when they get together, these cells form a sort of cellular memory, or methylation state. This methylation state is passed on between generations and determines how cells in 1 family will act in response to environmental challenges and how those cells will respond when similar challenges arise in another family member.
When methylation is induced in a cell, the result may be a whole gamut of changes on the cell surface and in the biochemical pathways within the cell. This causes alterations in gene function and a corresponding response physically. There are many ways that Epigenetic’s Science presents the science of Epigenetics. By way of instance, each chapter includes an informative section covering among the most frequent Epigenetic changes that exist in all people: puberty. The chapters include;”Growthal Sensitivity,””Mutations at Birth,”” hormonal changes,””perinatal development,””adolescent-onset diabetes,” and”nutrition.” I enjoyed each of these and found them to be quite interesting and educational.
As you know, during adolescence, the body increases its production of estrogen (in anticipation of future pregnancy), and then, produces DHT (which stands for”dihydrotestosterone”). DHT subsequently binds to the hair follicles, which makes it difficult for nutrients to reach the roots. This causes baldness in men and a condition called”male pattern baldness” Interestingly, this is not the only cause of hair loss, as there are other environmental and genetic factors that contribute to hair loss. Epigenetic science goes a step further and suggests that these other causes of hair loss may also be influenced by methylation, so future study might shed even more light on Epigenetic’s Science.
The next topic that Epigenetic’s Science touches on is the impact that diet has on the body. In particular, Epigenetic’s Science goes into detail about the impact that diet has on rats, rodents, and other organisms. To begin with, one interesting finding was that when the worm C. elegans has been given a high fat diet, it became diabetic and obese. Interestingly, the lab animals also lost muscle mass, which is suggestive of insulin resistance. In another experiment, the laboratory animals were put on a special sort of diet where they only received food which contained carbohydrates; they lost body fat fairly quickly.
So as to understand what’s happening here, you must have a look at the Epigenetic’s Science methodology. Basically, they are growing yeast in lab cultures and watching what happens. After the yeast grows to a certain point, it is going to replicate and thus create a new production of yeast cells. In cases like this, the generation of cells was used to study insulin resistance, something that we humans possess.
Needless to say, there are additional Epigenetic’s Science techniques that they use, such as gene regulation and the study of cancerous tumors. In actuality, they have recently launched a successful clinical trial in which they’re trying to treat Alzheimer’s disease in mice. As exciting as that may seem, it is not your everyday normal cancer therapy. This study shows they are able to control and regulate cells and halt the growth of cancerous tumors.
Besides diabetes, Epigenetic’s Science may be used for other kinds of diseases and ailments, such as Parkinson’s, arthritis, Multiple Sclerosis, and even cancer. Needless to say, these studies are extremely small so we don’t have much of a sense of what they will mean for human health. Still, it is an exciting and very promising prospect. Just think, one day you could have the ability to grow your own cells for immune system support and energy production; essentially creating your very own drug factory!