Epigenetic’s Science is written by award winning author, Raoul Pedretta. Good bye, genetically encoded genes… the first book in the exciting new field of epigenetic biology for general readers. The surging new science of epigenetic genetics offers a veritable cornucopia of new insights into our own bodies and minds – some unsettling, some reassuring. The assumption of Epigenetic’s Science is that environmental exposures can have long lasting effects on cellular function. Some of these effects are not very easy to reverse and the authors describe how”epigenetic inheritance” can result in such disorders as cancer, Alzheimer’s disease and Parkinson’s. They also describe the surprising effect of”epigenetic pollution,” environmental contaminants that are not detected by regular testing and that could cause serious health problems.
Like all living systems, cells are constantly changing and grow, divide and die. All cells require a continuous supply of energy, and this process is initiated by a process referred to as”mimetic induction”. Through natural selection, positive mutations accumulate over generations, and when they get together, these cells form a sort of cellular memory, or methylation state. This methylation state is passed on between generations and decides how cells in 1 family will behave in response to environmental challenges and how those cells will react when similar challenges arise in another family member.
When methylation is induced in a cell, the result can be a whole gamut of changes on the cell surface and in the biochemical pathways inside the cell. This causes alterations in gene function and a corresponding reaction on the body. There are many ways that Epigenetic’s Science presents the science of Epigenetics. By way of instance, each chapter includes an informative section covering among the most frequent Epigenetic changes which exist in all people: puberty. The chapters comprise;”Growthal Sensitivity,””Mutations in Birth,”” hormonal changes,””perinatal development,””adolescent-onset diabetes,” and”nutrition.” I enjoyed each of them and found them to be very interesting and educational.
As you know, during adolescence, the body increases its production of estrogen (in anticipation of future pregnancy), and then, produces DHT (which stands for”dihydrotestosterone”). DHT then binds to the hair follicles, making it difficult for nutrients to reach the roots. This causes baldness in a condition called”male pattern baldness.” Interestingly, this is not the only cause of hair loss, as there are other genetic and environmental factors that contribute to hair loss. Epigenetic science goes a step further and suggests that these other causes of hair loss may also be affected by methylation, so future study may shed more light on Epigenetic’s Science.
The next topic that Epigenetic’s Science touches on is the impact that diet has on the body. Specifically, Epigenetic’s Science goes into detail about the impact that diet has on rats, rodents, and other organisms. To begin with, one interesting finding was that when the worm C. elegans has been given a high fat diet, it became diabetic and obese. Interestingly, the lab animals also lost muscle mass, which is suggestive of insulin resistance. In another experiment, the lab animals were put on a particular sort of diet where they only received food which contained carbohydrates; they lost body fat fairly quickly.
In order to understand what’s going on here, you have to have a look at the Epigenetic’s Science methodology. Basically, they’re growing yeast in lab cultures and watching what happens. After the yeast grows to a certain point, it will replicate and thus create a new production of yeast cells. In this case, the generation of cells was used to study insulin resistance, something that we humans have.
Of course, there are other Epigenetic’s Science techniques they use, including gene regulation and the study of cancerous tumors. In actuality, they have recently launched a successful clinical trial where they’re attempting to treat Alzheimer’s disease in mice. As exciting as that may seem, it’s not your regular normal cancer therapy. This study shows that they are able to control and regulate cells and stop the growth of cancerous tumors.
In addition to diabetes, Epigenetic’s Science may be used for other types of diseases and conditions, such as Parkinson’s, arthritis, Multiple Sclerosis, and even cancer. Of course, these studies are extremely small so we do not have much of a sense of what they will mean for human health. Still, it’s an exciting and very promising prospect. Just think, one day you could be able to grow your own cells for immune system support and energy production; essentially creating your own drug factory!