Epigenetic’s Science is written by award winning author, Raoul Pedretta. Good bye, genetically encoded genes… the first book in the exciting new field of epigenetic biology for general readers. The surging new science of epigenetic genetics provides a veritable cornucopia of fresh insights into our bodies and minds – some unsettling, some reassuring. The assumption of Epigenetic’s Science is the fact that environmental exposures can have long lasting effects on cellular function. Some of these effects are not so easy to reverse and the authors describe how”epigenetic inheritance” can result in such disorders as cancer, Alzheimer’s disease and Parkinson’s. They also describe the surprising effect of”epigenetic pollution,” environmental contaminants that are not detected by standard testing and that can cause severe health problems.
Like all living systems, cells are constantly changing and grow, divide and die. All cells require a constant supply of energy, and this process is initiated by a process referred to as”mimetic induction”. Through natural selection, favorable mutations accumulate over generations, and if they get together, these cells form a sort of cellular memory, or methylation state. This methylation state is passed between generations and decides how cells in one family will act in response to environmental challenges and how those cells will react when similar challenges arise in another family member.
When methylation is induced in a cell, the result may be a whole gamut of changes on the cell surface and in the biochemical pathways inside the cell. This results in alterations in gene function and a corresponding response on the body. There are many ways in which Epigenetic’s Science presents the science of Epigenetics. By way of example, each chapter includes an informative section addressing one of the most common Epigenetic changes which exist in all people: puberty. The chapters comprise;”Growthal Sensitivity,””Mutations in Birth,”” hormonal changes,””perinatal development,””adolescent-onset diabetes,” and”nutrition.” I enjoyed each of them and found them to be quite interesting and educational.
As you know, during adolescence, the body increases its production of estrogen (in anticipation of future pregnancy), and then, produces DHT (which stands for”dihydrotestosterone”). DHT then binds to the hair follicles, making it difficult for nutrients to reach the roots. This causes baldness in a condition called”male pattern baldness” Interestingly, this isn’t the only cause of hair loss, as there are other environmental and genetic factors that contribute to hair loss. Epigenetic science goes a step further and suggests that these other causes of hair loss may also be influenced by methylation, so future study may shed more light on Epigenetic’s Science.
The next topic that Epigenetic’s Science touches on is the impact that diet has on the body. In particular, Epigenetic’s Science goes into detail concerning the impact that diet has on rats, rodents, and other organisms. To start with, one interesting finding was that when the worm C. elegans was given a high fat diet, it became obese and diabetic. Interestingly, the lab animals also lost muscle mass, which is indicative of insulin resistance. In another experiment, the laboratory animals were put on a special sort of diet where they just received food which contained carbohydrates; they lost body fat fairly quickly.
In order to understand what’s going on here, you have to have a look at the Epigenetic’s Science methodology. Basically, they’re growing yeast in lab cultures and watching what happens. After the yeast grows to a certain point, it is going to replicate and thus create a new production of yeast cells. In cases like this, the generation of cells has been used to study insulin resistance, something that we humans possess.
Needless to say, there are additional Epigenetic’s Science techniques that they use, such as gene regulation and the study of cancerous tumors. In actuality, they have recently launched a successful clinical trial in which they are trying to treat Alzheimer’s disease in mice. As exciting as that may sound, it’s not your regular normal cancer treatment. This study shows that they are able to control and regulate cells and halt the growth of cancerous tumors.
In addition to diabetes, Epigenetic’s Science may be used for other types of diseases and ailments, such as Parkinson’s, arthritis, Multiple Sclerosis, and even cancer. Of course, these studies are very small so we don’t have much of a sense of what they will mean for human health. Still, it’s an exciting and very promising prospect. Just think, one day you could be able to grow your own cells for immune system support and energy production; essentially creating your own drug factory!