Epigenetic’s Science is composed by award winning writer, Raoul Pedretta. Good bye, genetically encoded genes… the first book in the exciting new field of epigenetic biology for general readers. The surging new science of epigenetic genetics provides a veritable cornucopia of new insights into our own bodies and minds – some unsettling, some reassuring. The assumption of Epigenetic’s Science is that environmental exposures can have long lasting effects on cellular function. Some of these effects are not very easy to reverse and the authors describe how”epigenetic inheritance” can result in such illnesses as cancer, Alzheimer’s disease and Parkinson’s. They also clarify the surprising effect of”epigenetic pollution,” environmental contaminants which are not detected by regular testing and that could cause serious health problems.
Like all living systems, cells are constantly changing and grow, divide and die. All cells need a continuous supply of energy, and this procedure is initiated by a process called”mimetic induction”. Through natural selection, favorable mutations accumulate over generations, and if they get together, these cells form a sort of cellular memory, or methylation state. This methylation state is passed between generations and determines how cells in 1 family will act in response to environmental challenges and how those cells will respond when similar challenges arise in another family member.
When methylation is induced in a cell, the result may be a whole gamut of changes on the cell surface and in the biochemical pathways inside the cell. This causes alterations in gene function and a corresponding reaction physically. There are a number of ways in which Epigenetic’s Science presents the science of Epigenetics. By way of example, each chapter includes an informative section covering among the most frequent Epigenetic changes which exist in all of us: puberty. The chapters comprise;”Growthal Sensitivity,””Mutations at Birth,”” hormonal changes,””perinatal development,””adolescent-onset diabetes,” and”nutrition.” I enjoyed each of them and found them to be very interesting and educational.
As you know, during adolescence, the body increases its production of estrogen (in anticipation of future pregnancy), and in turn, produces DHT (which stands for”dihydrotestosterone”). DHT subsequently binds to the hair follicles, which makes it difficult for nutrients to reach the roots. This causes baldness in a condition known as”male pattern baldness” Interestingly, this is not the only cause of hair loss, as there are other genetic and environmental factors that contribute to hair loss. Epigenetic science goes a step further and suggests that these other causes of hair loss may also be influenced by methylation, so future research may shed more light on Epigenetic’s Science.
The next topic that Epigenetic’s Science touches on is the impact that diet has on the body. Specifically, Epigenetic’s Science goes into detail concerning the impact that diet has on mice, worms, and other organisms. To start with, one interesting finding was that when the worm C. elegans has been given a high fat diet, it became diabetic and obese. Interestingly, the laboratory animals also lost muscle mass, which is suggestive of insulin resistance. In another experiment, the lab animals were put on a special type of diet where they just received food which contained carbohydrates; they lost body fat fairly quickly.
So as to understand what is happening here, you must take a look at the Epigenetic’s Science methodology. Fundamentally, they are growing yeast in laboratory cultures and watching what happens. After the yeast grows to a certain point, it is going to replicate and thus create a new production of yeast cells. In this case, the creation of cells was used to study insulin resistance, something that we humans have.
Of course, there are other Epigenetic’s Science techniques that they use, including gene regulation and the analysis of cancerous tumors. In fact, they have recently established a successful clinical trial where they are trying to treat Alzheimer’s disease in mice. As exciting as that may sound, it’s not your everyday normal cancer treatment. This study shows they are able to control and regulate cells and halt the growth of cancerous tumors.
In addition to diabetes, Epigenetic’s Science may be used for other types of diseases and conditions, such as Parkinson’s, arthritis, Multiple Sclerosis, and even cancer. Of course, these studies are extremely small so we don’t have much of a sense of what they will mean for human health. Still, it’s an exciting and very promising prospect. Just think, one day you could have the ability to grow your own cells for immune system support and energy production; essentially creating your own drug factory!